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Sage is an herb. There are many species of sage. The two most common prevail sage (salvia officinalis) and spanish sage (salvia lavandulaefolia).
Sage might assist with chemical imbalances in the brain that trigger problems with memory and thinking skills. It might likewise change how the body uses insulin and sugar.
People commonly use sage for memory and believing skills, high cholesterol, and signs of menopause. It is also used for discomfort after surgical treatment, lung cancer, aching throat, sunburn, and many other conditions, however there is no good clinical proof to support these uses. 
Salvia officinalis has actually been utilized considering that ancient times for fending off evil, snakebites, increasing ladies’s fertility, and more. The romans referred to sage as the “holy herb,” and utilized it in their religious routines. Theophrastus wrote about 2 different sages, a wild undershrub he called sphakos, and a comparable cultivated plant he called elelisphakos. Pliny the older said the latter plant was called salvia by the romans, and used as a diuretic, an anesthetic for the skin, a styptic, and for other usages. Charlemagne recommended the plant for cultivation in the early midlifes, and during the carolingian empire, it was cultivated in monastery gardens. Walafrid strabo explained it in his poem hortulus as having a sweet scent and being useful for many human ailments– he went back to the greek root for the name and called it lelifagus.
The plant had a high credibility throughout the middle ages, with lots of expressions referring to its healing properties and worth. It was in some cases called s. Salvatrix (sage the savior). Dioscorides, pliny, and galen all recommended sage as a diuretic, hemostatic, emmenagogue, and tonic. Le menagier de paris, in addition to suggesting cold sage soup and sage sauce for poultry, advises infusion of sage for washing hands at table. John gerard’s herball (1597) states that sage “is singularly good for the head and brain, it quickeneth the senses and memory, strengtheneth the sinews, restoreth health to those that have the palsy, and taketh away shakey trembling of the members.” gervase markham’s the english huswife (1615) provides a recipe for a tooth-powder of sage and salt. It appears in recipes for 4 thieves vinegar, a mix of herbs which was expected to ward off the afflict. In past centuries, it was likewise used for hair care, insect bites and wasp stings, nervous conditions, mental conditions, oral preparations for swelling of the mouth, tongue and throat, and also to decrease fevers. 
Sage (salvia officinalis) is belonging to the mediterranean and naturalized throughout europe and north america. Referred to as garden sage, meadow sage, and real sage, this pungent herb belongs to the lamiaceae, or mint, household. The genus name is drawn from the latin salvare significance “to save.” the specific name officinalis suggests that sage was included on authorities lists of medicinal herbs. There are numerous types of sage, including clary sage (s. Sclarea) called because of its conventional use as an eyewash. Native americans used the roots and leaves of lyre-leafed sage (s. Lyrata l.), also known as cancerweed, as a salve for sores and in a tea to treat colds and coughs. Another types, called magnificent sage (s. Divinorum), a native of oaxaca, mexico, has actually been used for centuries by local shamans to attain modified states of awareness in healing rituals. There are many more garden varieties, including red or purple sage (s. Officinalis purpurascens), which is valued particularly for its medical purposes.
Sage prospers in full sun and well-drained soils, growing wild in some locations. It is a durable evergreen shrub with a deep taproot and an erect root stalk that produces woody, square, a little downy, branching stems that might reach a height of 4 feet (1.2 m). This familiar garden seasonal has long, light-green leaf stalks that bear simple opposite lance- or oval-shaped leaves. The strong and flexible leaves are veined, with a velvet-like rather crinkled texture and might grow to 2 in (5.1 cm) long in some ranges. Leaf margins look like a great embroidery finish with rounded minutely toothed edges. They are a gray-green on the top and lighter on the underside. The whole plant is highly fragrant, with a familiar pungency. Fresh leaves are bitter to the taste. Sage blossoms in the middle of summertime with little white, blue, or purple flowers. 
Basic requirements sage is a grows best in a well draining, abundant, clay loams with a ph in between 6.5 and 7.0. It should be planted completely sun, although some afternoon shade is endured. Sage plants require warm temperatures and ample sunshine in order to produce a high necessary oil content in the leaves. Propagation sage is usually propagated from seed, although both cuttings, departments and air layering is likewise successfully practiced. The planting website ought to be warm, dry and secured from wind. Seeds must be planted after all danger of frost has actually passed leaving 23 cm (9 in) between seeds. Fertilizer may be contributed to the soil prior to planting to aid development. Plants ought to be thinned to a final spacing of 45 cm (18 in). General care and maintenance sage plants ought to be pruned in early spring to promote new growth, or after flowering in the summertime. In addition to an application at planting, sage will gain from a side dressing of fertilizer 6 to 8 weeks after planting. Sage will become very woody within 3-4 years of planting and should be changed with brand-new plants. Collecting sage is finest collected right before flowering when the essential oil material of the leaves is highest. Sage needs to be collected by cutting the top 20 cm (8 in) of tender development with a sharp knife. Business fields may be collected by trimming however the highest quality product is accomplished by collecting only the leaves. 
Culinary sage types
The two main types of sage that are grown for their cooking uses consist of ‘berggarten ‘, or standard german sage, and the ever-popular ‘broadleaf ‘. While many individuals prefer to grow garden sage for cooking and its rich taste, broadleaf sage has a milder flavor, making it more suitable for marinading or adding to dishes and even cheese.
Garden sage is a durable perennial if you reside in hardiness zones 5-8 in the united states. It’s likewise resistant to insects and illness, so while you will require to eliminate small pests from the plant, it will not need much work from you to keep it healthy.
Likewise called: cooking sage, garden sage.
Scientific name: salvia officinalis.
Common sage leaves
Typical sage is a popular herb that is grown for both medical and culinary usages. It’s an easy-to-grow seasonal plant that can handle the majority of the harsher climates in the northern united states, as well as in colder areas.
It grows finest in raised beds with clayey soils in full sun to partial shade. Make sure it has complete drain. You ought to also search for excellent air flow around this plant to help avoid insects such as spider mites from destroying it or contaminating it with illness.
Also called: culinary sage.
Taxonomic name: salvia nemorosa ‘hot world’ an excellent plant to add to your veggie garden if you like matching fresh herbs with meals. The leaves can be utilized in both savory meals or desserts. This range of sage is also a good option if there are children (or animals) in your home because it has a milder taste than other types of sage. It also works well for pickling and flavoring oils, vinegars, butters and cheeses.
Scientific names: salvia officinalis ‘aurea’ and salvia officinialis ‘icterina’.
Golden sage has a less pungent taste than typical garden sage, and oftentimes has a slight citrus taste.
Golden sage does not fare extremely well in cooler environments and tends to be more conscious modifications in light or temperature than other types of sage. These garden varieties tend to be more sensitive to other insects and diseases also. However it is durable to about 20 degrees fahrenheit but can grow back from the roots if exposed to cooler temperatures.
Scientific name: perovskia atriplicifolia.
Russian sage is a lovely and aromatic blooming plant, but it can also be grown for cooking purposes. Belonging to russia, main asia and turkey, this seasonal herb is durable in usda zones 4 through 9 with a preference for zones 5 through 8. It has long flowering periods that face fall or winter and often reseeds itself the following spring.
The colors of russian sage flowers and leaves are mainly shades of purple. As a perennial, they can mature to 2 feet high with 2-inch long leaves growing in opposite pairs on the stem. The blossoms are normally violet to pinkish or purplish but might likewise be white.
Herbalists consider this plant slightly astringent and typically utilize it as a hair wash for dry or brittle hair. It is also effective in alleviating swelling of your mucus membranes, such as those found in the throat or mouth and nasal passages.
An infusion of russian sage has been utilized to deal with colds, sore throats and coughs when contributed to drinks such as tea.
Likewise referred to as: italian fragrant sage.
Taxonomic name: salvia officinalis ‘italian’.
Italian sage has big violet flowers with grey leaves. This range of culinary sage isn’t typically utilized for medicinal purposes, and it is a great choice if you wish to grow it for ornamental reasons. It matures to 2 feet high with opposite, ovate leaves that are about 1 inch in length.
Likewise called: salvia cypria.
Scientific names: salvia fruticosa.
Typical usages: this type of sage is belonging to the mediterranean area and is used mainly for ornamental factors. It matures to 3 feet tall with slim stems and dark green leaves. Its blue-purple flowers are typically utilized in arrangements and dried flower arrangements.
Greek sage is hardy in usda zones 5 through 9 and chooses to grow in full sun. It is a member of the mint family, so it can self-sow if offered adequate water.
Greek sage represent 50-95% (https://en.wikipedia.org/wiki/salvia_fruticosa) of the dried sage sold in north america, so to say it’s popular is an understatement.
Likewise called: scarlet salvia.
Scientific name: salvia splendens.
A special range of sage with vibrant red or purple flowers, this plant has an extremely aromatic fragrance that can be used to make a variety of herbal products. The growing tips are the most potent part of the plant, but you can also harvest them for use in sachets or other fragrant products. You can even dry and crush the leaves to develop your own potpourri.
Plants will reach around 2 feet high and expanded into a thick bush with their timeless oval green leaves. Like many perennials, you should cut down on water during the winter season when temperature levels drop below freezing.
Also referred to as: sweet sage.
Scientific name: salvia elegans.
This variety gets its name from the sweet smell it has when it flowers. Pineapple sage likewise grows well as an ornamental herb with small purple flowers and green leaves. You can utilize this range to make both a tea and cast or harvest the leaves for later usage.
Common uses for this plant consist of helping indigestion, decreasing discomfort connected with menstrual cramps, calming signs of stress and anxiety and helping you get a restful night’s sleep.
Pineapple sage is durable in usda zones 5 through 9 with a preference for zones 7 through 8. It is an annual flowering plant that can grow up to 4 feet tall and 2 feet broad. It has soft green leaves that are slightly serrated, giving it an unique appearance when compared to other plants in the salvia genus.
Pineapple sage is popular for its fragrant purple flowers with yellow centers but also makes an appealing decorative plant due to its dark green foliage and low-growing stature. The blossoms will appear from late summertime into fall or early winter on this hardy annual. They have a pineapple aroma that brings in bees and butterflies while including color to your garden beds during those months when lots of other blooming herbs fail to do so.
The small flowers are densely compacted with their purplish-red petals radiating from a yellow center. The plant itself will grow up to 4 feet tall, however it can also expand into a broader bush with some pruning and correct care.
Taxonomic name: salvia apiana.
White sage has silvery gray leaves and is frequently utilized as the common “sage burning” sage. Native to the southwestern areas of the united states and mexico. It is generally dried for ritualistic usage, burning as a smudge stick. White sage has a strong, pine-like aroma with a smokey finish. It is extremely valued for ceremonial usage by many native people.
The majority of ranges of white sage are not advised for cooking use because they tend to have more of a burnt taste than other ranges. White sage is likewise really sturdy, and can be grown in zones five to nine.
Taxonomic name: salvia farinacea.
Mealycup sage is belonging to texas and the desert areas of brand-new mexico. The leaves are blue-green or grey, with downy hairs below, and grow close together along the stems that can grow between 12 and 24 inches tall. Mealycup sage is also called texas tarragon due to the fact that it tastes like its french cousin when utilized in cooking. Herbalists use this plant to assist soothe indigestions, reduce stress and treat diarrhea.
The flowers on the mealycup sage are lilac-blue, white or pink relying on the variety you select. This durable perennial grows finest in usda zones 8 through 11 but will flourish in zone 6 if given the right amount of water. You can cut back on the amount you give it during the cold weather when temperature levels drop below freezing. Just don’t enable the plant to wilt totally.
Mealycup sage must be planted in a sunny area in either complete or partial sun and watered often. Nevertheless, this specific variety doesn’t succeed with overwatering– keep the soil somewhat dry between watering sessions. This is specifically real if utilizing a drip watering system– too much water will kill your plant off rather quickly. If you utilize sprinklers, wait up until after sundown so the leaves have time to fully dry before morning dew appears.
The seeds for mealycup sage are white and grow within pods that are generally around 1 inch.
Mexican bush sage
Taxonomic name: salvia leucantha.
Mexican bush sage
This variety of sage is native to mexico and main america. It grows between 2 and 3 feet high and has deeply colored, dark green foliage. Mexican bush sage is often utilized as a border plant in the landscape due to its ability to grow on high slopes and stand up to hot weather conditions with regular watering.
The small purple flowers flower from july through september on this durable seasonal plant however you can also gather leaves for tea or drying when it flowers so the plant remains healthy.
You might find that pinch back your mexican bush sage every couple of years throughout early spring at around 10 inches tall if you choose it as simply a decorative flower because they are extremely large bushes once they get to a specific size.
Taxonomic name: artemisia berggardiana.
This variety of sage is typically utilized for ornamental functions because of its attractive gray-green leaves. It grows in between 1 and 2 ′ high with a spread of as much as 3 ′. As the name recommends, berggarten sage grows finest in an environment zone 7 or higher but will do alright in zones 5 through 9 if provided the right amount of water– it doesn’t like to dry entirely!
The flowers flower blue from mid-july into august on this long lasting seasonal plant, however you can also harvest fresh leaves throughout summer season for use in your cooking productions so the plant stays healthy. If you pinch the tips off of your berggarten sage every couple of years in early spring at about 8 inches high, you can encourage it to grow bushier and thicker.
Likewise known as: wood sage.
Scientific name: salvia nemorosa.
Woodland sage is a perennial plant that grows to about 3 feet in height and has green leaves with purple markings. The plant can be used as a border for open woods or planted near taller plants. The fragrance of the blossoms is stated to attract bees, butterflies, and birds.
Forest sage spreads by rhizomes, and while they do not trigger any damage, they do grow on top of the ground. For this reason, forests sage is frequently grown in containers or raised beds. These plants can be grown in usda zones 4 through 8 and are fairly dry spell tolerant throughout the summer season.
Forest sage is typically used for medicinal purposes. It has actually been known to deal with anxiousness, vomiting, and diarrhea. The leaves are likewise utilized for teas in some cultures as a remedy for colds, coughs, and fevers.
It can be grown outdoors or as part of an indoor garden but is more often found growing outdoors near the woods or other gardens where it tends to flourish finest. This plant is best grown from seed and it is essential not to overwater or fertilize woodland sage plants. 
Advantages of sage
Sage is a staple herb in numerous foods around the globe.
Its other names include typical sage, garden sage and salvia officinalis. It belongs to the mint household, together with other herbs like oregano, rosemary, basil and thyme.
Sage has a strong fragrance and earthy taste, which is why it’s normally used in percentages. Even so, it’s packed with a variety of essential nutrients and substances.
Sage is also utilized as a natural cleaning agent, pesticide and routine object in spiritual sage burning or smudging.
This green herb is available fresh, dried or in oil form– and has numerous health benefits.
Here are 12 surprising health benefits of sage.
High in a number of nutrients
Sage loads a healthy dose of minerals and vitamins.
One teaspoon (0.7 grams) of ground sage contains:.
- Calories: 2
- Protein: 0.1 grams
- Carbs: 0.4 grams
- Fat: 0.1 grams
- Vitamin k: 10% of the
- Referral daily consumption (rdi)
- Iron: 1.1% of the rdi
- Vitamin b6: 1.1% of the rdi
- Calcium: 1% of the rdi
- Manganese: 1% of the rdi
As you can see, a small amount of sage loads 10% of your day-to-day vitamin k needs (2trusted source).
What’s more, this aromatic spice houses caffeic acid, chlorogenic acid, rosmarinic acid, ellagic acid and rutin– all of which play a role in its advantageous health results.
Because it’s consumed in small amounts, sage offers just small amounts of carbs, calories, protein and fiber.
Summary sage is
Rich in nutrients– particularly vitamin k– regardless of being low in calories. One.
Teaspoon (0.7 grams) boasts 10% of your everyday vitamin k requirements.
Packed with anti-oxidants
Antioxidants are molecules that assist strengthen your body’s defenses, neutralizing potentially harmful free radicals that are connected to chronic illness.
Sage consists of over 160 distinct polyphenols, which are plant-based chemical compounds that act as antioxidants in your body.
Chlorogenic acid, caffeic acid, rosmarinic acid, ellagic acid and rutin– all discovered in sage– are linked to remarkable health advantages, such as a lower risk of cancer and enhanced brain function and memory.
One research study found that drinking 1 cup (240 ml) of sage tea twice day-to-day significantly increased antioxidant defenses. It likewise reduced both total cholesterol and “bad” ldl cholesterol, along with raised “great” hdl cholesterol.
Summary sage is
Filled with anti-oxidants that are linked to numerous health advantages, including.
Improved brain function and lower cancer threat.
May assistance oral health
Sage has antimicrobial impacts, which can neutralize microbes that promote dental plaque.
In one research study, a sage-based mouthwash was revealed to efficiently kill the streptococcus mutans bacteria, which is infamous for triggering dental cavities.
In a test-tube research study, a sage-based vital oil was shown to kill and halt the spread of candida fungus albicans, a fungus that may also cause cavities.
One review kept in mind that sage might deal with throat infections, dental abscesses, contaminated gums and mouth ulcers. However, more human research study is needed to make extensive recommendations.
Has antimicrobial homes that may kill microorganisms that motivate the growth.
Of oral plaque.
May ease menopause signs
Throughout menopause, your body experiences a natural decrease in the hormonal agent estrogen. This can cause a large range of unpleasant symptoms.
Symptoms consist of hot flashes, extreme sweating, vaginal dryness and irritability.
Typical sage was generally utilized to decrease menopause signs.
It’s believed that compounds in sage have estrogen-like properties, enabling them to bind to certain receptors in your brain to help enhance memory and treat hot flashes and extreme sweating.
In one research study, everyday use of a sage supplement substantially reduced the number and strength of hot flashes over 8 weeks.
May help in reducing the intensity and frequency of menopause symptoms, such as hot
Flashes and irritation.
May lower blood glucose levels
The leaves of common sage have been utilized traditionally as a solution against diabetes.
Human and animal research study indicates that it may help lower blood glucose levels.
In one research study, sage extract lowered blood glucose levels in rats with type 1 diabetes by triggering a particular receptor. When this receptor is triggered, it can help clear excess complimentary fatty acids in the blood, which in turn improves insulin level of sensitivity.
Another research study in mice with type 2 diabetes discovered that sage tea imitates metformin– a drug recommended to manage blood glucose in individuals with the same disease.
In human beings, sage leaf extract has been shown to lower blood glucose and improve insulin sensitivity with a comparable impact as rosiglitazone, another anti-diabetes drugs.
However, there is still inadequate proof to advise sage as a diabetes treatment. More human research is needed.
Sage may lower blood sugar levels by increasing insulin level of sensitivity, more human research study is needed.
May support memory and brain health
Sage can assist support your brain and memory in several ways
For one, it’s packed with compounds that can serve as antioxidants, which have actually been shown to buffer your brain’s defense system.
It also appears to halt the breakdown of the chemical messenger acetylcholine (ach), which has a function in memory. Ach levels appear to fall in alzheimer’s disease.
In one research study, 39 participants with moderate to moderate alzheimer’s disease taken in either 60 drops (2 ml) of a sage extract supplement or a placebo daily for 4 months.
Those taking the sage extract carried out better on tests that determined memory, analytical, reasoning and other cognitive abilities.
In healthy adults, sage was revealed to enhance memory in low doses. Greater doses also elevated mood and increased alertness, calmness and contentedness.
In both more youthful and older adults, sage appears to enhance memory and brain function.
Show that sage might improve memory, brain function and signs of alzheimer’s.
May lower ‘bad’ ldl cholesterol
Every minute, more than a single person in the us dies from heart disease.
Numerous other human studies illustrate a comparable effect with sage extract.
May secure versus specific cancers
Cancer is a leading cause of death in which cells grow unusually.
Interestingly, animal and test-tube research studies demonstrate that sage might fight specific types of cancer, including those of the mouth, colon, liver, cervix, breast, skin and kidney.
In these studies, sage extracts not only suppress the development of cancer cells but likewise promote cell death.
While this research study is encouraging, human research studies are required to figure out whether sage is effective at combating cancer in people.
And animal research study recommend that sage may battle specific cancer cells, though.
Human research study is required.
Other possible health advantages
Sage and its substances are connected to several other health advantages.
However, these benefits have actually not been thoroughly researched.
May alleviate diarrhea: fresh sage is a.
Traditional remedy for diarrhea. Test-tube and animal studies discovered that.
It contains substances that may reduce diarrhea by unwinding your diet.
May assistance bone health: vitamin k,
Which sage provides in large quantities, plays a role in bone health. A deficiency in this vitamin.
Is connected to bone thinning and fractures.
May battle skin aging: a number of test-tube
Studies suggest that sage substances might assist combat indications of aging, such as wrinkles.
Has actually been connected to other possible health benefits, such as alleviating diarrhea,.
Supporting bone health and combatting skin aging.
Easy to contribute to your diet plan
Sage is available in a number of types and can be used in a variety of methods.
Fresh sage leaves have a strong fragrant taste and are best used sparingly in meals.
Here are some ways you can add fresh sage to your diet:.
- Sprinkle as a garnish on soups.
- Mix into a stuffing in roast meals.
- Integrate sliced entrusts butter to make sage butter.
- Add chopped leaves to tomato sauce.
- Serve it with eggs in an omelet.
Dried sage is typically preferred by cooks and comes ground, rubbed or in whole leaves.
Here are some methods you can utilize dried sage:.
- As a rub for meats.
- As a flavoring for roasted vegetables.
- Combined with mashed potatoes or squash for earthy flavor.
You can likewise buy sage items, such as sage tea and sage extract supplements.
Summary sage is
Exceptionally flexible and easy to contribute to soups, stews and baked dishes. It’s.
Available fresh, dried or ground. 
Possible adverse effects
When taken in as a spice in food, sage is considered safe for adults and children.
Health care professionals usually agree that:.
Sage ought to be safe when taken in medical quantities for no more than 2 months.
Sage may be risky when it’s taken in high doses or for a long period of time. Some types of sage, including typical sage (salvia officinalis), include a chemical called thujone. Too much thujone can trigger seizures and harm the liver and nervous system.
Sage applied to the skin is perhaps safe when utilized for approximately one week.
Sage vital oil, breathed in as aromatherapy, need to be safe. Like some other essential oils, sage oil can be toxic and ought to never ever be taken orally. Even when used topically, the oil should be watered down or it could cause rash or irritation.
Sage can likewise make anticonvulsant drugs less effective if used in excess, consisting of phenobarbital, mysoline (primidone), depakote (valproic acid), neurontin (gabapentin), tegretol (carbamazepine), and dilantin (phenytoin).
The extreme use of sage if you’re taking diabetes medications can trigger a possibly serious drop in blood sugar, causing hypoglycemia. If you utilize sage pills or extracts, never consume more than the advised dosage on the item label. Sage medications must be utilized with care in people with impaired kidney function.
Inform your healthcare provider about any medications you’re taking, consisting of herbal treatments like sage, so that you’re completely knowledgeable about the possible interactions and risks. 
Doses of 300 and 600 mg of dried sage leaf have been examined in state of mind and cognitive performance research studies. A standardized s. Officinalis ethanolic extract at a dose of 333 mg was utilized in a research study assessing its effects on memory and attention in healthy older volunteers. A typical dosage has actually been referred to as 4 to 6 g/day of the sage leaf. 
Drying medications (anticholinergic drugs) interaction ranking: moderate be cautious with this combination. Talk with your health provider.
Common sage (salvia officinalis) and spanish sage (salvia lavandulaefolia) might increase levels of particular chemicals in the body that work in the brain, heart, and in other places. Some drying medications called “anticholinergic drugs” can likewise these very same chemicals, but in a different way. These drying medications might decrease the impacts of these sage species, and these sage types might decrease the effects of drying medications.
A few of these drying medications consist of atropine, scopolamine, some medications utilized for allergic reactions (antihistamines), and some medications used for anxiety (antidepressants).
Estrogens interaction rating: moderate be cautious with this combination. Talk with your health provider.
Geraniol, a chemical in spanish sage (salvia lavandulaefolia), might have a few of the same impacts as estrogen. Nevertheless, geraniol discovered in spanish sage isn’t as strong as estrogen tablets. Taking spanish sage in addition to estrogen tablets may decrease the results of estrogen tablets.
Some estrogen tablets consist of conjugated equine estrogens (premarin), ethinyl estradiol, estradiol, and others.
Medications altered by the liver (cytochrome p450 2c19 (cyp2c19) substrates) interaction ranking: moderate beware with this combination. Talk with your health service provider.
Some medications are altered and broken down by the liver. Sage may decrease how rapidly the liver breaks down some medications. Taking sage along with some medications that are broken down by the liver may increase the effects and side effects of some medications. Before taking sage as a medication, talk with your healthcare provider if you take any medications that are altered by the liver.
Some medications that are changed by the liver consist of omeprazole (prilosec), lansoprazole (prevacid), and pantoprazole (protonix); diazepam (valium); carisoprodol (soma); nelfinavir (viracept); and others.
Medications changed by the liver (cytochrome p450 2c9 (cyp2c9) substrates) interaction ranking: moderate be cautious with this combination. Talk with your health supplier.
Some medications are altered and broken down by the liver. Sage might reduce how rapidly the liver breaks down some medications. Taking sage in addition to some medications that are broken down by the liver can increase the impacts and negative effects of some medications. Before taking sage as a medicine, talk to your doctor if you take any medications that are altered by the liver.
Some medications that are altered by the liver consist of diclofenac (cataflam, voltaren), ibuprofen (motrin), meloxicam (mobic), and piroxicam (feldene); celecoxib (celebrex); amitriptyline (elavil); warfarin (coumadin); glipizide (glucotrol); losartan (cozaar); and others.
Medications altered by the liver (cytochrome p450 2d6 (cyp2d6) substrates) interaction score: moderate beware with this combination. Talk with your health company.
Some medications are changed and broken down by the liver. Sage might decrease how quickly the body breaks down some medications. Taking sage along with some medications that are altered by the liver can increase the impacts and negative effects of your medication. Prior to taking sage as a medication, speak with your healthcare provider if you take any medications that are altered by the liver.
Some medications that are altered by the body include amitriptyline (elavil), codeine, desipramine (norpramin), flecainide (tambocor), fluoxetine (prozac), ondansetron (zofran), tramadol (ultram), and others.
Medications changed by the liver (cytochrome p450 2e1 (cyp2e1) substrates) interaction rating: moderate be cautious with this mix. Talk with your health company.
Some medications are altered and broken down by the liver. Common sage might increase how quickly the liver breaks down some medications. Taking typical sage together with some medications that are altered by the liver might reduce the effects and negative effects of your medication. Prior to taking typical sage as a medication, speak with your doctor if you take any medications that are changed by the liver.
Some medications that are changed by the liver include acetaminophen, chlorzoxazone (parafon specialty), ethanol, theophylline, and substance abuse for anesthesia throughout surgery such as enflurane (ethrane), halothane (fluothane), isoflurane (forane), and methoxyflurane (penthrane).
Medications changed by the liver (cytochrome p450 3a4 (cyp3a4) substrates) interaction ranking: moderate beware with this combination. Talk with your health supplier.
Some medications are changed and broken down by the liver. Sage might decrease how rapidly the liver breaks down some medications. Taking sage together with some medications that are broken down by the liver might increase the effects and adverse effects of these medications. Before taking sage as a medicine, speak with your doctor if you are taking any medications that are altered by the liver.
Medications that might be affected consist of specific heart medications called calcium channel blockers (diltiazem, nicardipine, verapamil), cancer drugs (etoposide, paclitaxel, vinblastine, vincristine, vindesine), fungus-fighting drugs (ketoconazole, itraconazole), glucocorticoids, alfentanil (alfenta), cisapride (propulsid), fentanyl (sublimaze), lidocaine (xylocaine), losartan (cozaar), midazolam (versed), and others.
Medications for alzheimer’s disease (acetylcholinesterase (pains) inhibitors) interaction rating: moderate be cautious with this combination. Talk with your health service provider.
Typical sage (salvia officinalis) and spanish sage (salvia lavandulaefolia) might increase certain chemicals in the brain, heart, and elsewhere in the body. Some medications used for alzheimer’s disease also impact these chemicals. Taking these species of sage along with medications for alzheimer’s disease might increase impacts and negative effects of medications utilized for alzheimer’s disease.
Medications for diabetes (antidiabetes drugs) interaction ranking: moderate be cautious with this combination. Talk with your health provider.
Sage might reduce blood sugar. Diabetes medications are likewise utilized to lower blood sugar. Taking sage in addition to diabetes medications might trigger your blood sugar to go too low. Screen your blood sugar closely. The dosage of your diabetes medication might need to be changed.
Some medications used for diabetes consist of glimepiride (amaryl), glyburide (diabeta, glynase prestab, micronase), insulin, pioglitazone (actos), rosiglitazone (avandia), chlorpropamide (diabinese), glipizide (glucotrol), tolbutamide (orinase), and others.
Medications for hypertension (antihypertensive drugs) interaction rating: moderate beware with this mix. Talk with your health service provider.
Typical sage (salvia officinalis) seems to reduce blood pressure. Taking typical sage together with medications for high blood pressure may trigger your high blood pressure to go too low. On the other hand, spanish sage (salvia lavandulaefolia) may increase blood pressure. Taking spanish sage together with medications for hypertension may decrease the impacts of these medications.
Some medications for high blood pressure consist of captopril (capoten), enalapril (vasotec), losartan (cozaar), valsartan (diovan), diltiazem (cardizem), amlodipine (norvasc), hydrochlorothiazide (hydrodiuril), furosemide (lasix), and numerous others.
Medications moved by pumps in cells (p-glycoprotein substrates) interaction score: moderate be cautious with this combination. Talk with your health company.
Some medications are moved by pumps into cells. Typical sage (salvia officinalis) may make these pumps less active and increase just how much of some medications get soaked up by the body. This may increase the side effects of some medications.
Some medications that are moved by these pumps include etoposide, paclitaxel, vinblastine, vincristine, vindesine, ketoconazole, itraconazole, amprenavir, indinavir, nelfinavir, saquinavir, cimetidine, ranitidine, diltiazem, verapamil, corticosteroids, erythromycin, cisapride (propulsid), fexofenadine (allegra), cyclosporine, loperamide (imodium), quinidine, and others.
Medications used to prevent seizures (anticonvulsants) interaction ranking: moderate beware with this combination. Talk with your health provider.
Medications used to prevent seizures affect chemicals in the brain. Sage may likewise affect chemicals in the brain. By impacting chemicals in the brain, sage may reduce the effectiveness of medications utilized to prevent seizures.
Some medications used to prevent seizures consist of phenobarbital, primidone (mysoline), valproic acid (depakene), gabapentin (neurontin), carbamazepine (tegretol), phenytoin (dilantin), and others.
Sedative medications (benzodiazepines) interaction score: moderate be cautious with this mix. Talk with your health provider.
Common sage (salvia officinalis) might trigger sleepiness and sleepiness. Medications that trigger sleepiness and sleepiness are called sedatives. Taking common sage in addition to sedative medications might cause too much drowsiness.
A few of these sedative medications consist of clonazepam (klonopin), diazepam (valium), lorazepam (ativan), and others.
Sedative medications (cns depressants) interaction ranking: moderate be cautious with this mix. Talk with your health service provider.
Sage may trigger sleepiness and sleepiness. Medications that triggers drowsiness are called sedatives. Taking sage along with sedative medications may trigger excessive sleepiness.
Some sedative medications consist of clonazepam (klonopin), lorazepam (ativan), phenobarbital (donnatal), zolpidem (ambien), and others.
Numerous medications used for glaucoma, alzheimer’s illness, and other conditions (cholinergic drugs) interaction rating: moderate beware with this mix. Talk with your health provider.
Typical sage (salvia officinalis) and spanish sage (salvia lavandulaefolia) might increase certain chemicals in the brain, heart, and elsewhere in the body. Some medications used for glaucoma, alzheimer’s illness, and other conditions likewise affect these chemicals. Taking these types of sage with these medications may increase the opportunity of negative effects.
Some of these medications used for glaucoma, alzheimer’s disease, and other conditions include pilocarpine (pilocar and others), donepezil (aricept), tacrine (cognex), and others. 
- Pregnancy and lactation.
Use cautiously in:.
- Seizure disorders;
- Diabetes 
The goal of this paper is to examine the recent developments in the expedition of sage (salvia types) as phytotherapy and to show its potential as a healing representative. Salvia types may represent a natural, safe, and reliable treatment for numerous illness and their symptoms. In current decades, with the increase in pharmacological understanding about the advantageous results of sage, especially s. Officinalis, these organic medications with anti-bacterial, antioxidant, anti-inflammatory, totally free extreme scavenging, and antitumor activities have been found to be extremely reliable in the development of unique natural drugs to prevent, control, and treat numerous minor illness along with more major and complex diseases such as diabetes, alzheimer’s, and cancer. It must be kept in mind that clinicians need to remain cautious up until more guaranteed research studies show the safety, quality, and efficacy of s. Officinalis. For these factors, extensive medicinal and chemical experiments, together with human metabolic research studies need to be the focus of our future studies, and further potential of s. Officinalis needs to be used in new healing drugs and offer a basis for future research on the application of medical plants.