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Blushwood Berry or Fontainea picrosperma, typically referred to as the blushwood tree, is a rainforest tree in the family Euphorbiaceae endemic to Queensland in Australia, where it grows on the Atherton Tablelands. [1]
Overview
An anti-cancer drug known as EBC-46 has been established from an extract of the fruits of Fontainea picrosperma. Trials have actually shown that it has activity against four different kinds of tumours, consisting of basal-cell carcinoma, cancer malignancy, squamous cell cancer and breast adenocarcinoma. The fruits are toxic to people if eaten. [3]
Stem
Massive watery red exudate appearing rapidly in the blaze.
Leaves
Oil dots noticeable with a lens, nearly noticeable to the naked eye. Leaf blades about 7-15 x 2-5 cm. Petioles shallowly carried or flattened on the upper surface area, the margins angular or somewhat winged. Young shoots outfitted in pale yellowish hairs. Twig exudate like that in the blaze.
Flowers
Petals in male flowers about 5-6 mm long and about 7-8 mm long in female flowers. Petals densely white, tomentose. Disk orange. Preconceptions 10, radiating like octopus arms.
Fruit
Fruit about 25 mm long and about 20 mm diam. Endocarp rather thick, stellate in transverse section, frequently 5-pointed in transverse area.
Seedlings
Cotyledons broadly ovate, about 45-55 x 30-40 mm, 3-veined at the base. At the tenth leaf stage: leaves lanceolate to ovate, pinnacle acuminate, base obtuse, upper surface of leaf blade glabrous; oil dots little, indistinct, visible just with a lens. Seed germination time 26 to 58 days.
Distribution and Ecology
Endemic to NEQ, limited to the Atherton Tableland. Altitudinal variety from 700-1100 m. Grows as an understory tree in well developed tropical rain forest.
Nature and Notes
Fallen fruit eaten by Cassowaries and Musky Rat-kangaroos. [4]
This trees grow just and specifically In the far north-eastern part of Queensland Australia, in the rain forests grows the Blushwood Berry tree referred to as Hylandia Dockrillii.
It grows at high elevations of 400 to 1100 meters in the strong jungle at various places and reaches heights of up to 25 meters. Blushwood berries are the fruit of the Blushwood tree. The tree’s berries have has exceptional medical homes and its main component EBC-46 might take concern in repairing the body immune system and DNA harmed cells in the near future of holistic treatments.
Blushwood Berry
Chemical extracts from the berries of Australian blushwood tree (Hylandia dockrillii) have actually shown to be reliable in dealing with cancers such as melanoma and breast cancer. Blushwood berry trees are said to be solely seen in the rainforests of Far North Queensland, Australia. However, attempts to grow them in a greenhouse environment are being done.
EBC-46 Extract
Scientists have actually established a drug called EBC-46 from the substance extracts of blushwood berries which are stated to have anticancer homes. Researchers say that the preparation of the drug is an intricate strategy and human trials are presently being performed. The anticancer results of this berry were first reported in 2004.
What does it do?
It is believed that the drug acts straight, deprives the cancer cells off their oxygen supply, and likewise triggers the host immune action. Cancer cells exposed shriveling, shrinking, and cell death microscopically quickly after exposure to the drug.
EBC-46 triggers an enzyme called protein kinase C; nevertheless, mechanism involved is still unpredictable. Nearly 75% of preclinical trials exposed appealing outcomes with extremely little regression in 1-year follow-up duration and no adverse effects. The drug was tested in easily accessible growths; however, its function in metastatic growths is yet to be established. Stage 1 clinical human trials in cutaneous strong growths such as cancer malignancy squamous cell carcinoma (SCC), head and neck SCC, basal cell cancer, and Merkel cell carcinoma are underway. EBC-46 is a patented chemotherapeutic drug.
The seeds then goes through an extracting process, The EBC-46 component is drawn out from seeds compounds, made into liquid, solid capsules or powder. Finally it gets packaged in the UK’s best business. [5]
How Blushwood Berries Can Damage Cancer Cells Nearly Immediately
A research study performed at QIMR Berghofer Medical Research Study Institute in Queensland, Australia has actually just recently shed brand-new light on what could end up being the next big cancer treatment: the blushwood berry (Hylandia dockrillii). This naturally happening fruit consists of compounds that began exterminating cancer cells practically right away when studied in the laboratory.
Chemotherapy and radiation are poisonous and come with harsh adverse effects, typically making the ill feel much more ill. The recent research study on this fantastic berry could imply new, natural treatments for cancer on the horizon.
Blushwood Berries– Where they Originate from
Blushwood berries are the fruit of the blushwood tree, which is known to grow in only one region of the world: the rainforests of Far North Queensland, Australia.
These tropical trees are not discovered anywhere else on the world, however grow in abundance near Australia’s northeastern suggestion.
These specific trees need extremely niche conditions to flourish– conditions which can only be found in specific portions of Far North Queensland, Australia.
Considering their usefulness as proven by the most current cancer research published in PLOS One, some are questioning if they could be grown in a greenhouse environment, so that individuals all over the world could benefit from their cancer-killing properties.
Blushwood Berries– What type of Cancer they Get rid of
The researchers at QIMR Berghofer Medical Research Institute, headed by Dr. Glen Boyle, utilized a speculative drug produced from the seeds of blushwood berries called EBC-46. They used this drug to deal with spots of melanoma (the most fatal type of skin cancer) on dogs, cats and horses.
The subjects were detected by veterinarians and offered a poor prognosis, most being considered candidates for euthanasia prior to participating in the research study.
Exceptionally, these animals that had actually been on death’s door prior to the research study had their cancer malignancy growths vanish after treatment in the laboratory by Dr. Boyle and his team of researchers.
Growths were Gone within 2 days
When the EBC-46 was injected into the cancerous cells on the topics, the tumors responded by turning a dark color, then falling off.
The derivative from the blushwood berry is thought to cut off oxygen supply to the cancer cells, allowing for the elimination of tumors without the need for surgical treatment, chemotherapy or radiation treatment.
The researchers reported that most of the topics’ growths– formerly considered a lost bring on by vets– were gone within 2 days of being injected with EBC-46.
Under the microscope, the private cancer cells started shriveling up and dying within simple momentsof entering contact with the EBC-46.
What the Future of Cancer Treatment Could Be?
The discovery of the effectiveness of EBC-46 is interesting news in the world of cancer treatment.
D.r Boyle states the findings of the pre-clinical trials at QIMR Berghofer suggest the drug could be effective in human clients.
” In most cases the single injection treatment caused the loss of practicality of cancer cells within four hours, and ultimately ruined the growths.”.
Dr. Boyle says EBC-46 operate in part by activating a cellular reaction which effectively cuts off the blood supply to the growth. “In more than 70 per cent of pre-clinical cases, the reaction and remedy was long-term and enduring, with extremely little regression over a duration of 12 months.”.
” We should stress at this moment that EBC-46 will only be trialed in the short-term for growths which can be accessed by direct injection or topical application,” Dr Boyle said.
” There is no proof to recommend EBC-46 would be effective against metastatic cancers.”.
Further studies utilizing human individuals could serve to show the blushwood berry to be nature’s hidden cancer remedy. [6]
Human trials for potential cancer treatment unearthed in Australian jungle underway
Australian scientists are trialling the cancer-fighting properties in fruit from rainforest trees in Far North Queensland.
EBC-46 is a molecule discovered in the berries of the rain forest tree blushwood (fontainea picrosperma), which grows on the Atherton Tablelands.
” It’s a small particle which works with the body to destroy cancer, instead of being a chemo-therapy approach which can act against the body,” Dr Victoria Gordon, CEO of Q-Biotics, told TODAY.
She discussed the ingenious treatment worked by injecting the molecule into the tumour website.
” We get complete tumour damage in five to seven days, great healing … and no considerable adverse effects”.
The impacts EBC-46 has been trialled with animals, consisting of Dr Gordon’s 18-year-old animal dog who had an oral melanoma.
” We injected the drug (EBC-46) and it just appeared to liquefy (the tumour),” she said.
Early stages of human trials are underway, with 14 patients dealt with up until now.
” We’ve had no considerable side effects and great results in six tumour types”.
Dr Gordon stressed there is still a “a long, hard roadway ahead” before a pharmaceutical can be developed from the drug. [7]
Promising ‘cancer-cure’ berries removed sale for worry of hazardous home remedy poisoning
‘ Most of the times the single injection treatment caused the loss of viability of cancer cells within 4 hours, and ultimately ruined the tumours,’ lead researcher Dr Glen Boyle informed the ABC.
Sellers of the native tree are rushing to take the jungle variety off sale nevertheless, after fears that people could be poisoned trying to create homemade cancer treatments.
‘ Our concern was people were just going to grow it, get some fruit, crush it up and consume it,’ Roger Smith, supervisor of Yuruga Native Plant Nursery told the Cairns Post.
Researcher Steven Ogbourne of the University of Sunshine Coast states it’s not that easy, and a complex treatment is needed to draw out the cancer-fighting substance.
Human trials are currently being prepared for the promising drug. [8]
Conclusion
Fontainea picrosperma (Blushwood) are rare small shy spindly dioecious, wet enclosed rainforest understorey trees requiring canopy security. Some Fontaineas species make it through in hasher conditions than the Blushwood. F.venosa can grow to 60 feet compared to 15 feet for Blushwood that grows at 2,300 feet to 3,600 ft. Blushwoods hate a cool temperature level and require the nutrients, wetness and the security of a wet jungle. Alkaloids found in all Fontainea sap causes cancerous tumours to ablate, however there are just 200 of these native trees in the world, so you will not lawfully be able to import these plants into the USA out of Australia. [9]
Referrals
- https://en.wikipedia.org/wiki/Fontainea_picrosperma
- https://apps.des.qld.gov.au/species-search/details/?id=17128
- https://www.herbal-organic.com/en/herb/197290
- https://apps.lucidcentral.org/rainforest/text/entities/fontainea_picrosperma.htm
- https://www.blushwoodforest.co.uk/
- https://www.seychellesweekly.com/2016/February%2015,%202016/beaute-sante1_blushwood_berries.html
- https://www.9news.com.au/health/cancer-fighting-berry-discovered/781a0d81-28f2-4f61-ba56-7895bc3e51ce
- https://www.thatslife.com.au/fears-of-cancer-cure-home-remedy-poisoning
- https://www.daleysfruit.com.au/forum/blushwood2/
